News 3 min read

Discover the Pasteur Institute's major discoveries for 2024

Published the Updated

A gene therapy trial for childhood deafness. A malaria vaccine. Microbiome gene editing. Cancer immunotherapy. A key gene in embryonic development. Effective treatment for bronchiolitis. Indian Ocean temperatures for anticipating outbreaks... Here is an excerpt from our discoveries for 2024. You can also download the poster in PDF format at the bottom of the page.

 

First gene therapy trial in France to treat childhood deafness

The Audiogene trial aims to correct the deficiency in a gene responsible for congenital deafness to restore hearing, using pioneering research conducted at the Institut Pasteur.

Read the press release

 

A malaria vaccine that blocks infection

Malaria remains a major public health threat in tropical countries. A vaccine against the parasite Plasmodium vivax proves effective in limiting blood-stage infection.

Read the publication

 

Immunotherapy: new mechanism of action of anti-PD1 antibodies

These antibodies, injected into the bloodstream, do not just act on the tumor; they also act on the lymph nodes, where many immune responses begin, raising hopes for more effective cancer treatments.

Read the news

Immunofluorescence de sections de ganglions lymphatiques montrant l'expression de PD-1 (rouge), CD4 (vert), CD19 (bleu). Les cellules T auxiliaires folliculaires sont les principales cellules ciblées par l'anticorps anti-PD-1, dans les ganglions lymphatiq
 
Child in home quarantine at the window putting a medical mask on his sick teddy bear, for protection against viruses during coronavirus COVID-19 and flu outbreak.

Monoclonal antibody effective in preventing severe bronchiolitis cases

A study by the Institut Pasteur and Santé publique France demonstrates the efficacy of nirsevimab as a preventive measure against bronchiolitis in infants.

Read the press release

 

Knowing Indian Ocean surface temperature can help anticipate dengue outbreaks

This approach could be used to improve predictions about the magnitude of dengue outbreaks several months in advance. The indicator, based on temperature fluctuations at the surface of the Indian Ocean, can also be used for any other world region.

Read the press release

Femelle d'Aedes aegypti. Le moustique Aedes aegypti est vecteur de la dengue, du chikungunya, de la fièvre jaune et de zika.
 

Institut Pasteur actively involved in Paris 2024 Olympic and Paralympic Games

After demonstrating prior to the event that the tiger mosquito is capable of transmitting several diseases in the Greater Paris region, the Institut Pasteur plays a key role in safeguarding public health and safety at the 2024 Olympic and Paralympic Games. Several staff members are also involved in the Games as participants, volunteers or torch bearers!

Read the press release

 

Technological breakthrough in microbiome gene editing

The startup Eligo Bioscience – co-founded by Institut Pasteur laboratory head David Bikard, who is also the company’s scientific advisor – successfully edits the DNA of microbiome bacteria directly in the gut of a mouse model.

Read the news (in french)

Colon murin, bactéries et débris d'aliments
 
Bordetella pertussis

Institut Pasteur explains the resurgence of whooping cough in France in 2024

Genomic analysis of 70 bacterial isolates gives scientists a better understanding of the largest whooping cough outbreak in France for at least 25 years.

Read the news

 

First long-term remission from HIV infection observed after a bone marrow transplant

Romuald, the “Geneva patient”, is the only patient to experience HIV remission after receiving a bone marrow transplant without the CCR5-delta 32 mutation, known to make CD4 cells resistant to the virus.

Read the press release

Accumulation de particules de VIH à la surface d’une cellule infectée
 
Festuccia

Key gene drives early embryonic development

The Institut Pasteur discovers the crucial role of the gene NR5A2 in the first stages of embryonic development in mammals. In the absence of this gene, the embryo stops developing a few days after fertilization. This research sheds new light on a biological process that is not yet fully understood.

Read the news

 

Artificial intelligence used to select phages, a targeted alternative to antibiotics

Scientists develop an AI model capable of making a tailored selection of phages by analyzing the genome of targeted bacteria.

Read the press release

Bactériophages sur la bactérie Escherichia coli
 

 

 

 

Download the poster “The Institut Pasteur in 2024”

en_annual_report_2024_institut_pasteur poster