Immunotherapy Combo

This medication doesn’t work for everyone… but we’ve just figured out why!

Rituximab is a revolutionary immunotherapy that helps your immune system eliminate diseased B cells, the ones responsible for certain blood cancers and autoimmune diseases.

It works by marking these diseased cells, which your immune system’s “Pac-Man”-like cells (macrophages) can then devour.

But here’s the catch: These B cells often hide in the lymph nodes, too far away from the macrophages.
As a result, the treatment doesn’t always work.

Capucine Grandjean, a researcher at the Institut Pasteur, and her team tested a low dose of radiation therapy as a complementary treatment…

And the macrophages finally get close enough to the B cells to eliminate them! The treatment becomes effective again.

This is a major discovery that could change the lives of thousands of patients with blood cancers or autoimmune diseases.

When two treatments combine to make a difference.

(video in french, english subtitles available translated by AI)